Huang C, Ye H, Xu J, Liu J, Qu A
Dept. of Bioengineering, Huazhong Univ of Sci & Tech, Wuhan.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2000 Mar;17(1):63-5, 94.
In this study the effects of the extremely low frequency (ELF) magnetic fields on intracellular Ca2+ concentration ([Ca2+]i) of rat chromaffinoma PC-12 cells were examined by using a digital fluorescence image microscopy system. A 50 Hz, 100 microT sinusoidal ELF magnetic field increased [Ca2+]i to a marked level, whereas a static field or a field of higher frequency (2000 Hz) did not cause a [Ca2+]i increase. The magnetic field-induced [Ca2+]i rise was partly due to an influx of extracellular Ca2+ and partly due to the release of intracellular Ca2+ pool. It seemed likely that the Ca2+ transport ability of the cell membranes was increased by the 50 Hz magnetic field.
在本研究中，通过使用数字荧光图像显微镜系统，检测了极低频（ELF）磁场对大鼠嗜铬细胞瘤PC-12细胞内钙离子浓度（[Ca2+]i）的影响。50Hz、100微特斯拉的正弦ELF磁场使[Ca2+]i显著升高，而静磁场或更高频率（2000Hz）的磁场并未导致[Ca2+]i升高。磁场诱导的[Ca2+]i升高部分归因于细胞外Ca2+的内流，部分归因于细胞内Ca2+池的释放。50Hz磁场似乎增强了细胞膜的Ca2+转运能力。
