Valkenborgh P, Dequeker J, Gielen F, DE Geest H
Acta Cardiol. 1976;31(4):269-76.
Clinical and laboratory data of 25 patients with inflammatory joint disease and pericarditis or valvular heart disease are reviewed. The patients were divided in two groups: 11 presented pericarditis and 14 valvular heart disease. The patients studied presented a spectrum of diseases ranging from classical sero-positive rheumatoid arthritis to ankylosing spondylitis. Acute rheumatic fever was in no case the actual joint disease. In contrast to the patients with valvular heart disease nearly all patients with pericarditis were rheumatoid arthritis factor positive and signs of a generalized systemic disease with vasculitis were also more frequent. In the pericarditis group there was no sex difference in contrast to the valvular group where females were more often affected. The heart lesions were usually detected late in the course of the chronic joint disease. Valvular heart disease occurs not only in ankylosing spondylitis but also in rheumatoid arthritis, usually the sero-negative type. In the light of a survey of the literature, the pertinent findings are discussed.
回顾了25例患有炎性关节病并伴有心包炎或心脏瓣膜病患者的临床和实验室数据。患者被分为两组：11例患有心包炎，14例患有心脏瓣膜病。所研究的患者呈现出一系列疾病，从典型的血清阳性类风湿性关节炎到强直性脊柱炎。无一例患者的实际关节病为急性风湿热。与患有心脏瓣膜病的患者相比，几乎所有患有心包炎的患者类风湿因子呈阳性，且伴有血管炎的全身性疾病体征也更常见。心包炎组不存在性别差异，而瓣膜病组女性更常受累。心脏病变通常在慢性关节病病程后期才被发现。心脏瓣膜病不仅发生在强直性脊柱炎中，也发生在类风湿性关节炎中，通常为血清阴性类型。根据文献综述，对相关发现进行了讨论。
