Glacet-Bernard A, Kuhn D, Coscas F, Coscas G, Soubrane G
Clinique Ophtalmologique Universitaire de Créteil, 40, avenue de Verdun, 94000 Créteil.
J Fr Ophtalmol. 2000 Jun;23(6):576-81.
Subfoveal choroidal neovascularization is a main cause of blindness. The new surgical technique of macular translocation conceived by De Juan, with scleral shortening and without a retinotomy, allows to move the fovea away from the neovascular membrane with a low rate of complications. The first results obtained with this technique are presented here, in cases of submacular neovascularization due to age-related macular degeneration (AMD) or degenerative myopia.
The first 10 patients who were operated on with this technique presented with subfoveal neovascularization due to AMD (6 eyes) or myopia (4 eyes). The time period between the beginning of the disease and surgery was less than 3 months. Before and after surgery, a complete examination included fluorescein and ICG angiographies and OCT.
Visual acuity improved by 2 lines or more in 6 eyes (60%), was unchanged in 3 eyes (30%) and decreased in 1 eye. The improvement in vision seemed higher in myopia than in ARMD. Conversely, the mean foveal displacement was greater in ARMD than in myopia (1.2 disc diameter and 0.5 respectively). Laser photocoagulation has been performed in all patients after surgery. Main complications were retinal detachment (1 eye) and neovascularization at the site of transretinal injection (1 eye). Mean follow-up was 3 months.
Macular translocation with the technique described by De Juan allowed visual improvement in more than the half of the eyes with subfoveal neovascularization, resulting in a moderate rate of complications. Long term follow-up is necessary to confirm these results.
黄斑下脉络膜新生血管是导致失明的主要原因。由德胡安构思的黄斑转位新手术技术,通过巩膜缩短且无需视网膜切开术,能够将黄斑中心凹从新生血管膜处移开,并发症发生率较低。本文介绍了该技术在年龄相关性黄斑变性(AMD)或变性近视所致黄斑下新生血管病例中的首批手术结果。
首批接受该技术手术的10例患者,其中6例因AMD、4例因近视导致黄斑下新生血管。从疾病开始至手术的时间间隔小于3个月。手术前后均进行了包括荧光素和吲哚菁绿血管造影以及光学相干断层扫描(OCT)在内的全面检查。
6只眼(60%)视力提高2行或更多,3只眼(30%)视力无变化,1只眼视力下降。近视患者的视力改善似乎高于年龄相关性黄斑变性患者。相反,年龄相关性黄斑变性患者黄斑中心凹的平均移位大于近视患者(分别为1.2视盘直径和0.5视盘直径)。所有患者术后均进行了激光光凝治疗。主要并发症为视网膜脱离(1只眼)和经视网膜注射部位新生血管形成(1只眼)。平均随访时间为3个月。
采用德胡安描述的技术进行黄斑转位,使超过半数黄斑下新生血管眼的视力得到改善,并发症发生率适中。需要长期随访以证实这些结果。