Gentina T, Arbion F, Benard A, Strecker A
Service de pneumologie, Hôpital Victor Provo Roubaix, France.
Rev Pneumol Clin. 2000 Jun;56(3):209-12.
Dermatomyositis, an inflammatory muscle disease probably related to dysimmunity, is associated with character skin eruptions. Dermatomyositis is often associated with cancer (15 to 40% of cases depending on the series). All histological types and all cancer localizations observed in the general population can be associated with dermatomyositis. We report the case of a patient with dermatomyositis who developed small-cell lung cancer. There have been few descriptions of this association in the literature. Certain clinical features of dermatomyositis would be predictive of its paraneoplastic nature. Prognosis is very poor. Treatment is basically dictated by the underlying neoplasia.
皮肌炎是一种可能与免疫功能异常相关的炎性肌肉疾病，常伴有特征性皮肤疹。皮肌炎常与癌症相关（根据不同系列报道，病例占比为15%至40%）。普通人群中观察到的所有组织学类型和所有癌症定位都可能与皮肌炎相关。我们报告了一例患皮肌炎并发生小细胞肺癌的患者。文献中对这种关联的描述很少。皮肌炎的某些临床特征可能预示其副肿瘤性质。预后非常差。治疗基本上取决于潜在的肿瘤。
