Herrmann D N, Blaivas M, Wald J J, Feldman E L
Department of Neurology, University of Rochester, SMH 601 Elmwood Ave., Box 673, Rochester, New York 14642, USA.
Muscle Nerve. 2000 Jul;23(7):1133-6. doi: 10.1002/1097-4598(200007)23:7<1133::aid-mus20>3.0.co;2-e.
Granulomatous myopathies are rare. Most cases are associated with sarcoidosis. We report a case of granulomatous myopathy associated with primary biliary cirrhosis, pancytopenia, and thymoma. The literature in regard to granulomatous myopathy and its pathogenesis is reviewed. Intermittent pulsed intravenous methylprednisolone may be useful as maintenance therapy for granulomatous myopathy and other neuromuscular syndromes for patients intolerant of oral corticosteroids.
肉芽肿性肌病较为罕见。大多数病例与结节病相关。我们报告一例与原发性胆汁性肝硬化、全血细胞减少症及胸腺瘤相关的肉芽肿性肌病。本文对肉芽肿性肌病及其发病机制的相关文献进行了综述。对于不耐受口服糖皮质激素的患者，间歇性脉冲静脉注射甲基强的松龙可能作为肉芽肿性肌病及其他神经肌肉综合征的维持治疗方法。
