Shinokuma T, Seo K, Ishida H, Kawashima S, Muranaka K, Miyawaki H
Department of Anesthesiology, Fukuoka University Hospital.
Masui. 2000 Jun;49(6):608-10.
Bradycardia during propofol anesthesia is well known, but bradycardia after propofol anesthesia has not been studied well. We compared perioperative heart rates in patients who had undergone gynecological surgery under lumbar epidural anesthesia supplemented with light general anesthesia using isoflurane and nitrous oxide in oxygen (Group Iso, n = 25) with those who had received lumbar epidural anesthesia supplemented with propofol (Group Prop, n = 25). The heart rates for the Group Prop were significantly lower (P < 0.05) than those for the Group Iso after the induction of anesthesia up to 2 hours after surgery. Two patients in the Group Prop developed bradycardia below 50 bpm 1 and 2 hours after surgery. In one of them intravenous atropine was necessary to treat bradycardia. We conclude that more attention should be paid to postoperative as well as intraoperative bradycardia in patients who receive propofol.
异丙酚麻醉期间的心动过缓是众所周知的，但异丙酚麻醉后的心动过缓尚未得到充分研究。我们比较了在腰段硬膜外麻醉复合异氟烷和笑气吸入浅全身麻醉下行妇科手术的患者（异氟烷组，n = 25）与接受腰段硬膜外麻醉复合异丙酚的患者（异丙酚组，n = 25）围手术期的心率。异丙酚组在麻醉诱导后至术后2小时的心率显著低于异氟烷组（P < 0.05）。异丙酚组有2例患者在术后1小时和2小时出现心率低于50次/分钟的心动过缓。其中1例患者需要静脉注射阿托品来治疗心动过缓。我们得出结论，对于接受异丙酚麻醉的患者，术后以及术中的心动过缓都应给予更多关注。
