Prince M I, Thomas S H, James O F, Hudson M
Lancet. 2000 Jun 10;355(9220):2047-8. doi: 10.1016/S0140-6736(00)02354-0.
We report substantial reductions in the frequency of severe paracetamol hepatotoxicity locally and nationally after legislative limitations on its sale. These reductions were not explained by changes in referral patterns or use of N-acetylcysteine.
我们报告称,在对扑热息痛的销售进行立法限制后,当地和全国范围内严重扑热息痛肝毒性的发生率大幅下降。这些下降无法通过转诊模式的变化或N-乙酰半胱氨酸的使用来解释。