一种新型VO2+/阿司匹林复合物的合成、表征及生物活性
Synthesis, characterization and bioactivity of a new VO2+/aspirin complex.
作者信息
Etcheverry S B, Williams P A, Barrio D A, Sálice V C, Ferrer E G, Cortizo A M
机构信息
Cátedra de Bioquímica Patológica, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
出版信息
J Inorg Biochem. 2000 May 30;80(1-2):169-71. doi: 10.1016/s0162-0134(00)00026-x.
Abstract
A new VO2+ complex with salicylic acid acetate (Aspirin) of formula C18H18Cl2O12V2 was synthesized and characterized. Its biological effects upon cell proliferation, differentiation and promotion of tyrosine protein phosphorylation have been tested in two lines of osteoblast-like cells in culture.
摘要
合成并表征了一种分子式为C18H18Cl2O12V2的新的水杨酸醋酸酯（阿司匹林）VO2+配合物。已在两种培养的成骨样细胞系中测试了其对细胞增殖、分化以及酪氨酸蛋白磷酸化促进作用的生物学效应。
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