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[舒可捷(索高捷疗)在体外条件下对神经组织的作用]

[Effect of Solcoseryl on nerve tissue under in vitro conditions].

作者信息

Lindner G, Grosse G, Plonka G

出版信息

Z Mikrosk Anat Forsch. 1976;90(3):416-26.

PMID:1088564
Abstract

Explants from trigeminal ganglia and skin of chick embryos and hippocampus from fetal rats were cultivated in Maximow assembly in the presence of Solcoseryl (Solco AG, Basel), a blood extract of calf. Solcoseryl in vitro did not influence the regeneration of nerve fibers from CNS explants. A stimulatory effect of Solcoseryl in vitro by 1% concentration on the outgrowth of new processes in explants of PNS was demonstrated. It is discussed: under optimal concentration Solcoseryl may be important for the influence of the composition of the medium in which explants of the nerve system and skin are cultivated.

摘要

将来自鸡胚三叉神经节和皮肤以及胎鼠海马体的外植体在含有小牛血液提取物Solcoseryl(巴塞尔Solco AG公司)的Maximow培养装置中培养。体外实验中,Solcoseryl对中枢神经系统外植体神经纤维的再生没有影响。实验证明,1%浓度的Solcoseryl在体外对周围神经系统外植体新突起的生长有刺激作用。文中讨论了:在最佳浓度下,Solcoseryl对于培养神经系统和皮肤外植体的培养基成分的影响可能很重要。

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