Wood L V, Woodbine M
Zentralbl Bakteriol Orig A. 1979 Mar;243(1):74-81.
The chick embryo was used to investigate the pathogenicity of Listeria monocytogenes when inoculated into the air sac. One strain (NCTC 5214) of L. monocytogenes was found to be more virulent for chick embryos when grown at low temperatures, while another strain (NCTC 5105) did not produce this effect. This method was found to be reliable and reproducible and the chick embryo was found to be a more sensitive in vivo assay for virulence than the mouse.
利用鸡胚研究单核细胞增生李斯特菌接种到气囊肿后的致病性。发现单核细胞增生李斯特菌的一个菌株(NCTC 5214)在低温下生长时对鸡胚的毒性更强,而另一个菌株(NCTC 5105)则没有这种作用。该方法被证明是可靠且可重复的,并且发现鸡胚是一种比小鼠更敏感的体内毒力测定方法。