Ohayon M M, Priest R G, Zulley J, Smirne S
Sleep Disorders Clinic, Stanford University Medical Center, California 94305, USA.
J Nerv Ment Dis. 2000 Jun;188(6):340-8. doi: 10.1097/00005053-200006000-00004.
Confusional arousals, or sleep drunkenness, occur upon awakening and remain unstudied in the general population. We selected a representative sample from the United Kingdom, Germany, and Italy (N = 13,057) and conducted telephone interviews. Confusional arousals were reported by 2.9% of the sample: 1% (95% confidence interval: .8 to 1.2%) of the sample also presented with memory deficits (53.9%), disorientation in time and/or space (71%), or slow mentation and speech (54.4%), and 1.9% (1.7% to 2.1%) reported confusional arousals without associated features. Younger subjects (< 35 years) and shift or night workers were at higher risk of reporting confusional arousals. These arousals were strongly associated with the presence of a mental disorder with odds ratios ranging from 2.4 to 13.5. Bipolar and anxiety disorders were the most frequently associated mental disorders. Furthermore, subjects with Obstructive Sleep Apnea Syndrome (OSAS), hypnagogic or hypnopompic hallucinations, violent or injurious behaviors, insomnia, and hypersomnia are more likely to suffer from confusional arousals. Confusional arousals appears to occur quite frequently in the general population, affecting mostly younger subjects regardless of their gender. Physicians should be aware of the frequent associations between confusional arousals, mental disorders, and OSAS. Furthermore, the high occurrence of confusional arousals in shift or night workers may increase the likelihood of inappropriate response by employees sleeping at work.
混乱觉醒,即睡眠醉酒,发生在觉醒时,在普通人群中尚未得到充分研究。我们从英国、德国和意大利选取了一个具有代表性的样本(N = 13057)并进行了电话访谈。2.9%的样本报告有混乱觉醒:其中1%(95%置信区间:0.8%至1.2%)的样本还伴有记忆缺陷(53.9%)、时间和/或空间定向障碍(71%)或思维和言语迟缓(54.4%),1.9%(1.7%至2.1%)报告的混乱觉醒无相关特征。较年轻的受试者(< 35岁)以及轮班或夜班工作者报告混乱觉醒的风险更高。这些觉醒与精神障碍的存在密切相关,比值比在2.4至13.5之间。双相情感障碍和焦虑症是最常相关的精神障碍。此外,患有阻塞性睡眠呼吸暂停综合征(OSAS)、入睡或觉醒幻觉、暴力或伤害行为、失眠和嗜睡的受试者更易出现混乱觉醒。混乱觉醒似乎在普通人群中相当常见,主要影响较年轻的受试者,无论其性别如何。医生应意识到混乱觉醒、精神障碍和OSAS之间的频繁关联。此外,轮班或夜班工作者中混乱觉醒的高发生率可能会增加在工作中睡觉的员工做出不当反应的可能性。