Corrao G, Bagnardi V, Vittadini G, Favilli S
Department of Statistics, Faculty of Statistical Sciences, Chair of Medical Statistics and Epidemiology, University of Milan, Bicocca, Italy.
J Epidemiol Community Health. 2000 Aug;54(8):603-10. doi: 10.1136/jech.54.8.603.
To investigate the utility of capture-recapture methods to estimate prevalence of subjects with alcohol related disorders using multiple incomplete lists.
This was a cross sectional study of alcohol related disorders in a large community.
During 1997 identified cases with known alcohol related disorders were independently flagged by four sources (self help volunteering groups; psychiatric ambulatory; public alcohology service; hospital discharges).
381 records were flagged, corresponding to 349 individual cases from a target population resident in a northern Italy area.
The two sample capture-recapture estimates were clearly biased because of dependencies among sources. Estimates based on log-linear models showed prevalent counts ranged from 2297 (95% confidence intervals: 1524, 3794) to 2523 (95% confidence intervals: 1623, 4627) after adjustment for dependence among sources only or also for heterogeneity in catchability among age categories (< 50 and >/= 50 years), respectively.
The study suggests that capture-recapture is an appropriate approach for estimating prevalence of subjects with alcohol related problems who seek or need treatment and assistance when different lists of alcoholics can be obtained from different types of agencies involved with problematic use of alcohol. Critical factors are the complexity in case definition and the analysis of heterogeneity among people. Accurate estimates are needed to plan and evaluate public health interventions.
探讨捕获-再捕获方法在利用多个不完整列表估计酒精相关障碍患者患病率方面的效用。
这是一项针对大型社区中酒精相关障碍的横断面研究。
1997年期间,已知患有酒精相关障碍的确诊病例由四个来源独立标记(自助志愿者团体;精神科门诊;公共酒精学服务机构;医院出院记录)。
标记了381份记录,对应于意大利北部地区目标人群中的349例个体病例。
由于来源之间的相关性,两个样本捕获-再捕获估计值明显存在偏差。基于对数线性模型的估计显示,仅对来源之间的相关性进行调整后,患病率计数范围为2297(95%置信区间:1524, 3794);分别对年龄类别(<50岁和≥50岁)之间捕获能力的异质性进行调整后,患病率计数范围为2523(95%置信区间:1623, 4627)。
该研究表明,当可以从涉及酒精问题使用的不同类型机构获得不同的酗酒者列表时,捕获-再捕获是估计寻求或需要治疗及援助的酒精相关问题患者患病率的一种合适方法。关键因素是病例定义的复杂性以及人群异质性的分析。规划和评估公共卫生干预措施需要准确的估计值。