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使用捕获-再捕获法估计意大利北部某一地区的酒精相关问题的流行率。

Prevalence estimates of alcohol related problems in an area of northern Italy using the capture-recapture method.

机构信息

Local Health Authority (ASL) of Pavia, Department Social Health, Unit of Research and Evaluation, Pavia, Italy.

出版信息

Eur J Public Health. 2010 Oct;20(5):576-81. doi: 10.1093/eurpub/ckq038. Epub 2010 Apr 12.

Abstract

BACKGROUND

The alcohol-related problems (ARPs) are a relevant issue in public health and contribute to premature deaths and avoidable disease burden. The capture-recapture (C-R) method can be a useful tool to provide reliable estimates for populations with hidden nature such as subjects with ARP.

METHODS

C-R method was used to estimate the 'true count' of individuals with ARP using three independent health-related current databases in an area of northern Italy during 2007. To predict the frequency of unascertained cases, we constructed log linear models. The goodness-of-fit of a model was measured by the likelihood ratio test and the final model was selected using Akaike's Information Criterion. Confidence intervals (CIs) were calculated according to Hook and Regal.

RESULTS

Altogether 1014 subjects with ARP were directly identified from the three sources using the C-R method the estimated unknown population was 2729 subjects, giving a total of 3743 subjects with ARP (95% CI 3148-4504) and a prevalence of 8.24 (95% CI 7.97-8.50) per 1000 inhabitants aged >15 years. The analyses stratified for gender estimated 12.31/1000 (95% CI 11.85-12.77) men and 4.86/1000 (95% CI 4.58-5.14) women with ARP. Besides, the analysis calculated a prevalence of 14.99 per 1000 (95% CI 14.29-15.69) for males <50 years (1731), corresponding to the majority of subjects with ARP.

CONCLUSION

The C-R technique is useful to provide a more realistic picture of the size of ARP population. This has important implications both for future planning of service provision and for the way in which the impact of ARP interventions are evaluated.

摘要

背景

酒精相关问题(ARPs)是公共卫生中的一个重要问题,导致过早死亡和可避免的疾病负担。捕获-再捕获(C-R)方法可以成为一种有用的工具,为具有隐藏性质的人群(如 ARP 患者)提供可靠的估计。

方法

使用 C-R 方法,在意大利北部的一个地区,利用三个独立的健康相关当前数据库来估计 ARP 患者的“真实数量”。为了预测未确定病例的频率,我们构建了对数线性模型。模型的拟合优度通过似然比检验来衡量,最终模型通过赤池信息量准则来选择。置信区间(CIs)根据胡克和雷加尔计算。

结果

共使用 C-R 方法从三个来源直接确定了 1014 名 ARP 患者,估计未知人群为 2729 名,共 3743 名 ARP 患者(95%CI 3148-4504),患病率为 8.24(95%CI 7.97-8.50)每 1000 名年龄大于 15 岁的居民。按性别分层分析估计,男性中 ARP 患病率为 12.31/1000(95%CI 11.85-12.77),女性为 4.86/1000(95%CI 4.58-5.14)。此外,分析计算出年龄小于 50 岁(1731 人)的男性中 ARP 患病率为 14.99/1000(95%CI 14.29-15.69),占 ARP 患者的大多数。

结论

C-R 技术有助于更真实地了解 ARP 人群的规模。这对未来服务提供的规划以及评估 ARP 干预措施的影响方式都具有重要意义。

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