Levine M D, Camitta B M, Nathan D, Curran W J
J Pediatr. 1975 Jan;86(1):145-50. doi: 10.1016/s0022-3476(75)80728-1.
Bone marrow transplantation has been utilized for the treatment of severe aplastic anemia in a program at The Children's Hospital Medical Center. A protocol has been developed to help ensure that the interests and rightful claims of all involved parties will be taken into account. Three cases are presented. In one case all involved parties concurred with the plan for bone marrow transplantation. In a second case the prospective donor was deemed mentally incompetent to give truly informed consent for the procedure. In a third case the parents were unwilling to have their child undergo transplantation. The ethical issues raised in these cases suggest the need for further development of a moral technology to enhance decision-making competence and to aid in the recognition and application of the rights of children without impeding the advancement of pediatric medicine.
儿童医院医疗中心的一个项目已将骨髓移植用于治疗严重再生障碍性贫血。现已制定了一项方案，以确保所有相关方的利益和合法权益都能得到考虑。本文介绍了三个案例。在一个案例中，所有相关方都同意骨髓移植计划。在第二个案例中，预期捐赠者被认为精神上无行为能力，无法对该手术给出真正知情的同意。在第三个案例中，父母不愿意让他们的孩子接受移植。这些案例中提出的伦理问题表明，需要进一步发展一种道德技术，以提高决策能力，并有助于在不妨碍儿科学发展的情况下，认识和应用儿童的权利。
