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[早期同性性早熟揭示一名3岁刚果女孩患有幼年型颗粒细胞瘤]

[Early isosexual precocious pseudopuberty revealing a juvenile granulosa cell tumor in a 3-year-old Congolese girl].

作者信息

Mouko A, Moukassa D, Leroy X, Ibara J, Makosso E, Bikandou G, Kalengayi R M, Senga P

机构信息

Service de Pédiatrie Nourrissons, CHR de Brazzaville, Congo.

出版信息

Ann Pathol. 2000 May;20(3):245-8.

Abstract

We describe a juvenile granulosa cell tumor expressed by an early pseudopuberty occurring in a 3-year-old black child. Clinically, an endocrine syndrome was associated with a pelvic mass and ascites. Hyperoestrogenia and serum alphafetoprotein level were biologically detected. Histological examination showed typical microscopic features of a granulosa cell tumor. The patient is well four years after surgery. Growth and mental development are normal.

摘要

我们描述了一例发生在一名3岁黑人儿童的早期假性性早熟所表现出的青少年颗粒细胞瘤。临床上,一种内分泌综合征与盆腔肿块和腹水相关。从生物学角度检测到了高雌激素血症和血清甲胎蛋白水平。组织学检查显示出颗粒细胞瘤典型的微观特征。该患者术后四年情况良好。生长和智力发育正常。

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