Maidment I D
Hellesdon Hospital, Norwich, Norfolk, UK.
Acta Psychiatr Scand. 2000 Jul;102(1):3-11. doi: 10.1034/j.1600-0447.2000.102001003.x.
To review the literature regarding the use of fish oils in the treatment of psychiatric illness.
A Medline search was conducted in September 1999.
Five papers have investigated omega-3 fatty acids levels in depression. One study used omega-3 fatty acids as an adjunctive therapy in bipolar disorder. Four studies used fatty acids as an adjunctive therapy in schizophrenia.
There is a great deal of current research in this field. While omega-3 fatty acids levels may be lowered in depression, there are no data suggesting that omega-3 fatty acids are effective. One paper indicates that omega-3 fatty acids are effective in bipolar disorders. The data on schizophrenia are conflicting. Omega-3 and omega-6 fatty acids have proved effective. Most of the evidence suggests that the main effect is an improvement in negative symptoms. One recent study showed that omega-3 fatty acids had no effect on negative symptoms.
回顾有关鱼油用于治疗精神疾病的文献。
1999年9月进行了医学文献数据库（Medline）检索。
有五篇论文研究了抑郁症患者体内ω-3脂肪酸水平。一项研究将ω-3脂肪酸用作双相情感障碍的辅助治疗。四项研究将脂肪酸用作精神分裂症的辅助治疗。
该领域目前有大量研究。虽然抑郁症患者体内ω-3脂肪酸水平可能降低，但尚无数据表明ω-3脂肪酸有效。一篇论文指出ω-3脂肪酸对双相情感障碍有效。关于精神分裂症的数据相互矛盾。ω-3和ω-6脂肪酸已被证明有效。大多数证据表明主要作用是改善阴性症状。最近一项研究表明ω-3脂肪酸对阴性症状没有影响。
