Carson C C, Mulcahy J J, Govier F E
University of North Carolina, Chapel Hill, North Carolina, Wishard Memorial Hospital, Indianapolis, Indiana, and Mason Clinic, Seattle, Washington.
J Urol. 2000 Aug;164(2):376-80.
We performed a long-term multicenter study of the AMS 700CX 3-piece inflatable penile prosthesis, focusing on longevity, morbidity and patient satisfaction in men implanted up to 134 months with a median followup of 47.7 months.
We performed a large scale retrospective multicenter study in 2 phases. Phase 1 was a medical record review of 372 men who underwent implantation with the AMS 700CX penile prosthesis from 1987 to 1996 by 7 frequent penile prosthesis implanters. Phase 2 included a structured telephone interview of 207 patients by a neutral observer.
For the 372 men in phase 1 mean device mechanical reliability plus or minus standard deviation was 92.1% + or - 3.3% after 3 and 86.2% + or - 4.6% after 5 years. Patient age was 21 to 79 years (mean 57.6 + or - 11.0) at implantation. The etiology of erectile dysfunction was vascular in 27.7% of the cases, Peyronie's disease in 16.9%, diabetes mellitus in 12.9% and radical surgery in 11.6%. Of the men 55.6% received previous treatment for erectile dysfunction. Postoperative infection and device malfunction developed in 3.2% and 17.5% of the cases, respectively. Of the 207 men interviewed in phase 2, 86% still had an AMS 700CX penile prosthesis implanted, including 87.1% with erection suitable for coitus. Currently 79% of those with a device use it at least twice monthly and 88.2% would recommend an implant to a relative or friend.
The AMS 700CX penile implant produced suitable erection and excellent patient satisfaction at long-term followup in the majority of men. Implant reliability is excellent and postoperative morbidity is low.
我们对AMS 700CX三件套可膨胀阴茎假体进行了一项长期多中心研究，重点关注植入长达134个月且中位随访时间为47.7个月的男性患者的使用寿命、发病率和患者满意度。
我们分两个阶段进行了一项大规模回顾性多中心研究。第一阶段是对1987年至1996年期间由7位频繁进行阴茎假体植入手术的医生为372名男性植入AMS 700CX阴茎假体的病历进行回顾。第二阶段包括由一名中立观察员对207名患者进行结构化电话访谈。
在第一阶段的372名男性中，术后3年装置的机械可靠性平均为92.1%±3.3%，5年后为86.2%±4.6%。植入时患者年龄为21至79岁（平均57.6±11.0）。勃起功能障碍的病因中，血管性占27.7%，佩罗尼氏病占16.9%，糖尿病占12.9%，根治性手术占11.6%。55.6%的男性此前接受过勃起功能障碍治疗。术后感染和装置故障分别发生在3.2%和17.5%的病例中。在第二阶段接受访谈的207名男性中，86%仍植入有AMS 700CX阴茎假体，其中87.1%的勃起功能适合性交。目前，79%的有该装置的患者每月至少使用两次，88.2%的患者会向亲属或朋友推荐植入手术。
在大多数男性的长期随访中，AMS 700CX阴茎植入物产生了合适的勃起效果并具有出色的患者满意度。植入物可靠性极佳，术后发病率低。
