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硫氰酸盐介导的山羊乳过氧化物酶的抗真菌和抗菌特性。

Thiocyanate mediated antifungal and antibacterial property of goat milk lactoperoxidase.

作者信息

Benoy M J, Essy A K, Sreekumar B, Haridas M

机构信息

School of Biosciences, Mahatma Gandhi University, Kottayam.

出版信息

Life Sci. 2000;66(25):2433-9. doi: 10.1016/s0024-3205(00)80003-x.

Abstract

Goat milk lactoperoxidase was purified using CM-Sephadex-C-50 ion exchange chromatography and Sephadex G-100 gel filtration. The purified protein was found to have high antifungal and antibacterial activity in a thiocyanate-H2O2 medium. The results are relevant enough to suggest the exploitation of LP-thiocyanate-H2O2 system as an effective agent against many of the disease causing organisms in plants and animals.

摘要

采用CM - 葡聚糖凝胶C - 50离子交换色谱法和葡聚糖凝胶G - 100凝胶过滤法对山羊乳中的乳过氧化物酶进行了纯化。结果发现,纯化后的蛋白质在硫氰酸盐 - H2O2介质中具有较高的抗真菌和抗菌活性。这些结果足以表明,利用乳过氧化物酶 - 硫氰酸盐 - H2O2体系作为一种有效试剂来对抗动植物中许多致病生物是可行的。

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