轻度黄素单加氧酶3缺乏症的生化与分子研究 - Suppr

Suppr

超能文献

Biochemical and molecular studies in mild flavin monooxygenase 3 deficiency.

作者信息

Zschocke J, Mayatepek E

机构信息

Department of General Pediatrics, University Children's Hospital, Heidelberg, Germany.

出版信息

J Inherit Metab Dis. 2000 Jun;23(4):378-82. doi: 10.1023/a:1005647701321.

DOI:10.1023/a:1005647701321

PMID:10896299

Abstract

摘要

相似文献

Biochemical and molecular studies in mild flavin monooxygenase 3 deficiency.轻度黄素单加氧酶3缺乏症的生化与分子研究

J Inherit Metab Dis. 2000 Jun;23(4):378-82. doi: 10.1023/a:1005647701321.

Fish odour syndrome.鱼腥味综合征

Postgrad Med J. 2000 May;76(895):318-9. doi: 10.1136/pmj.76.895.318a.

Trimethylaminuria (fish odor syndrome) related to the choline concentration of infant formula.与婴儿配方奶粉胆碱浓度相关的三甲胺尿症（鱼腥味综合征）。

Pediatr Emerg Care. 2003 Apr;19(2):101-3. doi: 10.1097/00006565-200304000-00010.

[Fish odour--could be a sign of trimethylaminuria].[鱼腥味——可能是三甲胺尿症的迹象]

Ugeskr Laeger. 2010 Nov 22;172(47):3268-9.

Fish odor syndrome: a case report of trimethylaminuria.鱼腥味综合征：一例三甲胺尿症病例报告

Dermatol Online J. 2014 Jan 15;20(1):21260.

Mild trimethylaminuria caused by common variants in FMO3 gene.由FMO3基因常见变异引起的轻度三甲胺尿症。

Lancet. 1999 Sep 4;354(9181):834-5. doi: 10.1016/s0140-6736(99)80019-1.

A novel mutation in the flavin-containing monooxygenase 3 gene, FM03, that causes fish-odour syndrome: activity of the mutant enzyme assessed by proton NMR spectroscopy.一种导致鱼腥味综合征的含黄素单加氧酶3基因（FM03）的新型突变：通过质子核磁共振光谱法评估突变酶的活性。

Pharmacogenetics. 2000 Jul;10(5):439-51. doi: 10.1097/00008571-200007000-00007.

Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.导致日本人发生三甲基胺尿症的黄素单加氧酶 3（FMO3）基因突变。

Mol Genet Metab. 2012 Nov;107(3):330-4. doi: 10.1016/j.ymgme.2012.06.014. Epub 2012 Jul 1.

What have we here? A man or a fish?我们这儿有什么？一个人还是一条鱼？

Lancet. 2010 Nov 13;376(9753):1710. doi: 10.1016/S0140-6736(10)61151-8.

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.含黄素单加氧酶基因（FMO3）的突变会导致三甲胺尿症，这是一种解毒缺陷疾病。

Hum Mol Genet. 1998 May;7(5):839-45. doi: 10.1093/hmg/7.5.839.

引用本文的文献

Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease.三甲胺和三甲胺 N-氧化物，一种由含黄素单加氧酶 3（FMO3）介导的、与健康和疾病相关的宿主-微生物群代谢轴。

Drug Metab Dispos. 2016 Nov;44(11):1839-1850. doi: 10.1124/dmd.116.070615. Epub 2016 May 17.

Trimethylaminuria.三甲胺尿症

BMJ Case Rep. 2016 Apr 26;2016:bcr2015213742. doi: 10.1136/bcr-2015-213742.

Clinical utility gene card for: Trimethylaminuria - update 2014.三甲胺尿症临床实用基因卡 - 2014年更新版

Eur J Hum Genet. 2015 Sep;23(9). doi: 10.1038/ejhg.2014.226. Epub 2014 Oct 22.

Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.日本人群中含黄素单加氧酶3（FMO3）基因型与三甲胺尿症表型之间的关系。

Br J Clin Pharmacol. 2014 May;77(5):839-51. doi: 10.1111/bcp.12240.

Transient massive trimethylaminuria associated with food protein-induced enterocolitis syndrome.与食物蛋白诱导的小肠结肠炎综合征相关的短暂性大量三甲胺尿症。

JIMD Rep. 2014;12:11-5. doi: 10.1007/8904_2013_238. Epub 2013 Jul 3.

Clinical utility gene card for: trimethylaminuria.三甲胺尿症临床实用基因卡

Eur J Hum Genet. 2012 Mar;20(3). doi: 10.1038/ejhg.2011.214. Epub 2011 Nov 30.

Genetic polymorphisms of human flavin-containing monooxygenase 3: implications for drug metabolism and clinical perspectives.人类含黄素单加氧酶3的基因多态性：对药物代谢的影响及临床前景

Pharmacogenomics. 2007 Jun;8(6):635-43. doi: 10.2217/14622416.8.6.635.

本文引用的文献

Mild trimethylaminuria caused by common variants in FMO3 gene.由FMO3基因常见变异引起的轻度三甲胺尿症。

Lancet. 1999 Sep 4;354(9181):834-5. doi: 10.1016/s0140-6736(99)80019-1.

Two novel mutations of the FMO3 gene in a proband with trimethylaminuria.三甲胺尿症先证者中FMO3基因的两个新突变。

Hum Mutat. 1999;13(5):376-9. doi: 10.1002/(SICI)1098-1004(1999)13:5<376::AID-HUMU5>3.0.CO;2-A.

Transient trimethylaminuria in childhood.儿童期短暂性三甲胺尿症。

Acta Paediatr. 1998 Nov;87(11):1205-7. doi: 10.1080/080352598750031257.

Hum Mol Genet. 1998 May;7(5):839-45. doi: 10.1093/hmg/7.5.839.

Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome.含黄素单加氧酶3基因（FMO3）的错义突变是鱼腥味综合征的病因。

Nat Genet. 1997 Dec;17(4):491-4. doi: 10.1038/ng1297-491.

Individual differences in nicotine kinetics and metabolism in humans.人类尼古丁动力学和代谢的个体差异。

NIDA Res Monogr. 1997;173:48-64.

N-oxygenation of primary amines and hydroxylamines and retroreduction of hydroxylamines by adult human liver microsomes and adult human flavin-containing monooxygenase 3.成人肝脏微粒体和成人含黄素单加氧酶3对伯胺和羟胺的N-氧化作用以及羟胺的逆向还原作用

Chem Res Toxicol. 1996 Oct-Nov;9(7):1183-93. doi: 10.1021/tx9600614.

Recent studies on the structure and function of multisubstrate flavin-containing monooxygenases.近期关于含黄素多底物单加氧酶结构与功能的研究。

Annu Rev Pharmacol Toxicol. 1993;33:179-99. doi: 10.1146/annurev.pa.33.040193.001143.

The fish odour syndrome: biochemical, familial, and clinical aspects.鱼腥味综合征：生化、家族性及临床方面

BMJ. 1993 Sep 11;307(6905):655-7. doi: 10.1136/bmj.307.6905.655.

Expression in Escherichia coli of the flavin-containing monooxygenase D (form II) from adult human liver: determination of a distinct tertiary amine substrate specificity.成人肝脏含黄素单加氧酶D（II型）在大肠杆菌中的表达：确定独特的叔胺底物特异性

Chem Res Toxicol. 1993 Jul-Aug;6(4):425-9. doi: 10.1021/tx00034a006.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验