Davidson J, Gilbert R, Irish J, Witterick I, Brown D, Birt D, Freeman J, Gullane P
Sunnybrook & Women's College Health Sciences Centre, Department of Otolaryngology, Toronto, Ontario.
Head Neck. 2000 Aug;22(5):449-54; discussion 454-5. doi: 10.1002/1097-0347(200008)22:5<449::aid-hed1>3.0.co;2-l.
It is common practice for a panendoscopy to be included in the evaluation of patients with mucosal head and neck malignancies. Whether this intervention is efficient or cost-effective has not been established in our patient population.
Two hundred twenty-four patients with squamous cell carcinoma involving the oral cavity, pharynx, larynx, or neck were evaluated prospectively with panendoscopy and chest x-ray with or without barium swallow. One hundred fifty-four patients had newly diagnosed tumors and 70 were previously diagnosed and currently undergoing symptom-directed investigations.
The incidence of synchronous primary tumors was 2.6% (4 of 154); pulmonary, 1.3%; head and neck mucosa, 1.3%; and esophageal, 0%. There was no associated morbidity.
Although there was no associated morbidity, our head and neck oncology group is of the opinion that routine panendoscopy is not warranted. Specific indications for this investigation are discussed.
在对头颈部黏膜恶性肿瘤患者进行评估时，常规进行全面内镜检查是常见做法。在我们的患者群体中，这种干预措施是否有效或具有成本效益尚未确定。
对224例患有累及口腔、咽、喉或颈部的鳞状细胞癌患者进行了前瞻性评估，采用全面内镜检查以及胸部X线检查，部分患者还进行了或未进行吞钡检查。154例患者为新诊断的肿瘤，70例为先前已诊断且目前正在接受针对症状的检查。
同步原发性肿瘤的发生率为2.6%（154例中的4例）；肺部，1.3%；头颈部黏膜，1.3%；食管，0%。未出现相关并发症。
尽管未出现相关并发症，但我们的头颈部肿瘤学团队认为常规全面内镜检查并无必要。文中讨论了该项检查的具体适用情况。
