Pelloni A, Gertsch P
Service de chirurgie, Ospedale San Giovanni, Bellinzona.
Schweiz Med Wochenschr. 2000 Jun 10;130(23):871-7.
A review of the literature shows that tumour seeding after fine-needle biopsy of a hepatocellular carcinoma is observed in 0.6 to 5.1% of cases. This complication may be detected between one and 72 months after needle biopsy, and the lapse of time between biopsy and diagnosis of recurrence is influenced neither by the tumour grading nor by the diametre of the needle and number of puncture. In most cases, needle biopsy is not necessary to establish the surgical indication and may compromise the result of surgery; it should therefore be restricted to exceptional cases. Because needle-tract seeding may be the sole tumour recurrence, close follow-up of patients who have undergone pre-operative needle biopsy is important for early detection and possible cure.
文献综述表明，肝细胞癌细针穿刺活检后肿瘤种植在0.6%至5.1%的病例中可见。这种并发症可在穿刺活检后1至72个月被发现，活检与复发诊断之间的时间间隔不受肿瘤分级、针的直径及穿刺次数影响。在大多数情况下，穿刺活检对于确定手术指征并非必要，且可能影响手术结果；因此应仅限于特殊情况。由于针道种植可能是唯一的肿瘤复发，对接受术前穿刺活检的患者进行密切随访对于早期发现及可能的治愈至关重要。
