LaClaire L, Facklam R
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Antimicrob Agents Chemother. 2000 Aug;44(8):2130-2. doi: 10.1128/AAC.44.8.2130-2132.2000.
Facklamia spp. are gram-positive cocci, arranged in short chains or diplos, and resemble viridans streptococci on 5% sheep blood agar. Eighteen strains representing four species of Facklamia were isolated from blood cultures, an abscess, bone, cerebrospinal fluid, gall bladder, vaginal swab, and one unknown source. Cultures were tested against 15 antimicrobial agents by using the broth microdilution MIC method. Reduced susceptibilities to the beta lactams, erythromycin, clindamycin, trimethoprim-sulfamethoxazole, and tetracycline were found. These results indicate that the susceptibilities of the Facklamia species are varied and that some strains have resistance patterns which may present difficulty in managing systemic infections in patients.
法克勒菌属为革兰氏阳性球菌,呈短链状或双球状排列,在5%绵羊血琼脂上类似草绿色链球菌。从血培养、脓肿、骨、脑脊液、胆囊、阴道拭子及一个未知来源中分离出代表法克勒菌四个种的18株菌株。采用肉汤微量稀释MIC法对培养物进行了15种抗菌药物的测试。发现对β-内酰胺类、红霉素、克林霉素、甲氧苄啶-磺胺甲恶唑和四环素的敏感性降低。这些结果表明,法克勒菌种的敏感性各不相同,一些菌株具有耐药模式,这可能给患者系统性感染的治疗带来困难。