Pannone B K, Wolin S L
Departments of Cell Biology and Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06536, USA.
Curr Biol. 2000 Jun 29;10(13):R478-81. doi: 10.1016/s0960-9822(00)00552-2.
Ring-shaped structures containing seven Sm or Sm-like proteins are stable components of several small nuclear ribonucleoprotein particles that function in pre-mRNA splicing. Recent reports describe a role for a distinct complex of seven Sm-like proteins in a very different process: mRNA degradation.
含有七种Sm或Sm样蛋白的环形结构是几种小核核糖核蛋白颗粒的稳定组成部分，这些颗粒在mRNA前体剪接中发挥作用。最近的报道描述了一种由七种Sm样蛋白组成的独特复合物在一个截然不同的过程中的作用：mRNA降解。
