Pomeroy S L, Kim J Y
Department of Neurology, Division of Neuroscience, Children's Hospital, Boston, Massachusetts 02115, USA.
Ment Retard Dev Disabil Res Rev. 2000;6(1):41-6. doi: 10.1002/(SICI)1098-2779(2000)6:1<41::AID-MRDD6>3.0.CO;2-V.
Differentiation of neurons within the central nervous system occurs by the combined effects of intrinsic genetic programs and epigenetic stimuli. Disorders causing mental retardation and other abnormalities of higher cortical function arise by disturbances of the normal developmental sequence. MRDD Research Reviews 6:41-46, 2000.
中枢神经系统内神经元的分化是由内在遗传程序和表观遗传刺激的联合作用所导致的。引起智力迟钝和其他高级皮质功能异常的疾病是由正常发育序列的紊乱所引发的。《MRDD研究评论》第6卷:41 - 46页,2000年。