Carrillo Domínguez A
Servicio de Endocrinología, Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria.
Rev Clin Esp. 2000 May;200(5):257-60. doi: 10.1016/s0014-2565(00)70625-4.
To prospectively evaluate the incidence of type 1 diabetes mellitus in patients up to 30 years of age in the Canary Islands during 1995 and 1996.
The population under study consisted of 744,444 inhabitants in the 0-29 year old group and 302,293 in the 0-14 year old group. The capture-recapture method was used for estimating the probability of ascertainment. Hospital records and endocrinologists' reports were the primary source, whereas reports from the Canary Diabetes Association reports and sales of blood glucose monitors were the secondary source.
A total of 223 new cases of type 1 diabetes mellitus were detected during the study period. The degree of ascertainment was 90.1%. The observed incidence rates were 23.2 per 100,000 per year for the 0-14 year old group and 9.2 per 100,000 per year for the 15-29 year old group. The overall incidence rate was 15 per 100,000 per year for the entire group. The highest incidence was found in the 10-14 year old group. The incidence in males was higher than in females, and particularly significant in the 15-29 year old group. No seasonal onset pattern was detected.
A high rate of incidence of type 1 diabetes mellitus was observed in this study in children aged less than 15 years living in the Canary Islands.
前瞻性评估1995年和1996年加那利群岛30岁及以下患者1型糖尿病的发病率。
研究人群包括0至29岁组的744,444名居民以及0至14岁组的302,293名居民。采用捕获-再捕获法估算确诊概率。医院记录和内分泌科医生的报告为主要来源,而加那利糖尿病协会的报告和血糖仪销售数据为次要来源。
研究期间共检测到223例新的1型糖尿病病例。确诊率为90.1%。0至14岁组的观察发病率为每年每10万人23.2例,15至29岁组为每年每10万人9.2例。整个组的总体发病率为每年每10万人15例。发病率最高的是10至14岁组。男性发病率高于女性,在15至29岁组尤为显著。未检测到季节性发病模式。
本研究观察到加那利群岛15岁以下儿童1型糖尿病的发病率较高。