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[呼吸道过敏症的流行病学:当前数据]

[Epidemiology of respiratory allergies: current data].

作者信息

Charpin D, Raherison C, Dutau H, Taytard A

机构信息

Service de Pneumologie-Allergologie, Hôpital Nord, Marseille.

出版信息

Rev Mal Respir. 2000 Feb;17(1 Pt 2):139-58.

Abstract

Respiratory allergic diseases include seasonal allergic rhinitis or hay fever, perennial allergic rhinitis and allergic asthma. Prevalence of asthma is difficult to assess through epidemiological questionnaires. In France hay fever roughly affects 6% of children and 18% of teenagers and nasal allergies, more than one fourth of young adults. Prevalence of asthma is equal to 10 to 15% in teenagers and 7 to 9% in young adults. Risk factors include genetic as well as environmental factors. The role of the former have been exemplified in family studies, especially twin studies, and surveys of inbred populations. Environmental factors can be allergic or non-allergic. The influence of allergenic exposure on sensitization, occurrence and severity of respiratory allergic disease is well documented. The triggering influence of non-allergenic factors on established allergic diseases is also clear. In contrast, their implication in allergic sensitization and occurrence of allergic diseases need to be clarified.

摘要

呼吸道过敏性疾病包括季节性过敏性鼻炎或花粉症、常年性过敏性鼻炎和过敏性哮喘。哮喘的患病率很难通过流行病学调查问卷来评估。在法国,花粉症大约影响6%的儿童和18%的青少年,而鼻过敏则影响超过四分之一的年轻人。青少年哮喘的患病率为10%至15%,年轻人为7%至9%。风险因素包括遗传因素和环境因素。前者的作用在家族研究中得到了例证,特别是双胞胎研究以及对近亲繁殖人群的调查。环境因素可以是过敏性的或非过敏性的。变应原暴露对呼吸道过敏性疾病的致敏、发生和严重程度的影响已有充分记录。非变应原性因素对已确诊的过敏性疾病的触发影响也很明显。相比之下,它们在过敏性致敏和过敏性疾病发生中的作用尚需阐明。

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