类风湿关节炎药物治疗期间的全身元素组成：一项初步研究。
Whole body elemental composition during drug treatment of rheumatoid arthritis: a preliminary study.
作者信息
Kennedy A C, Boddy K, Williams E D, Elliott A T, Harvey I, Holloway I, Haywood J K
出版信息
Ann Rheum Dis. 1979 Apr;38(2):137-40. doi: 10.1136/ard.38.2.137.
Abstract
Thirty-two female patients with rheumatoid arthritis were divided into 3 groups and treated for 6 months with prednisolone, depot tetracosactrin, or indomethacin. Their whole body content of calcium, phosphorus, and nitrogen was measured before and after 3 and 6 months' treatment by in-vivo neutron activation analysis. No significant changes in these body elements were observed as a result of the treatments. The average amounts of calcium, phosphorus, and nitrogen were lower than normal in these patients, a finding consistent with the frequent observation of osteoporosis and muscle wasting in rheumatoid arthritis.
摘要
32名类风湿性关节炎女性患者被分为3组，分别用泼尼松龙、长效四氢促皮质素或吲哚美辛治疗6个月。在治疗3个月和6个月前后，通过体内中子活化分析测量了她们全身的钙、磷和氮含量。治疗后这些身体元素未观察到显著变化。这些患者体内钙、磷和氮的平均含量低于正常水平，这一发现与类风湿性关节炎中经常观察到的骨质疏松和肌肉萎缩现象一致。
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引用本文的文献
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Total body calcium in rheumatoid arthritis: effects of disease activity and corticosteroid treatment.类风湿关节炎患者的全身钙含量：疾病活动度及皮质类固醇治疗的影响
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