Khafagy M, el-Bolkainy M N, Barsoum R S, el-Tatawy S
J Urol. 1975 Mar;113(3):314-6. doi: 10.1016/s0022-5347(17)59470-7.
Ten patients underwent radical cystectomy and ileocecal bladder reconstruction for carcinoma of the bladder. The ileocecal region was used as an artificial bladder, its valve protecting the kidneys from back pressure exerted by the external urethral sphincter. The ureters were anastomosed to the ileal part and the cecum was anastomosed to the prostatic urethra in 7 men and to the bladder neck in 2 women and 1 man. Two patients died postoperatively. All patients had perfect control of micturition during the day. Those in whom the bladder neck was preserved were also fully continent at night. The remaining patients had a minor degree of nocturnal enuresis with only a few drops of urine voided involuntarily during sleep. All patients feel the desire to void when the bladder is full. Voiding cystograms in all patients did not reveal reflux in the ureters. IVP's done up to 11 months postoperatively showed preservation and improvement of kidney function and configuration. Followup cystometric studies and serum electrolyte determinations are under investigation.
10例患者因膀胱癌接受了根治性膀胱切除术及回肠膀胱重建术。回肠盲肠区域被用作人工膀胱，其瓣膜可保护肾脏免受外尿道括约肌施加的反压影响。输尿管与回肠部分进行吻合，7例男性患者的盲肠与前列腺尿道吻合，2例女性患者和1例男性患者的盲肠与膀胱颈吻合。2例患者术后死亡。所有患者白天排尿控制良好。保留膀胱颈的患者夜间也完全无尿失禁。其余患者有轻度夜间遗尿，睡眠时仅不自主地漏出几滴尿液。所有患者膀胱充盈时都有排尿欲望。所有患者的排尿膀胱造影均未显示输尿管反流。术后长达11个月的静脉肾盂造影显示肾功能及形态得以保留并有所改善。正在对随访膀胱测压研究及血清电解质测定进行调查。
