Marneros A, Pillmann F, Haring A, Balzuweit S
Klinik und Poliklinik für Psychiatrie und Psychotherapie Martin-Luther-Universität Halle-Wittenberg.
Fortschr Neurol Psychiatr. 2000 Apr;68 Suppl 1:S22-5.
Psychotic disorders with acute onset, a dramatic and polymorphous symptomatology and rapid resolution have been described in different countries and by different psychiatric schools. They have been called cycloid psychosis, bouffée délirante, psychogenic psychosis or good prognosis schizophrenia. ICD-10 has given an operational definition under the name "acute and transient psychotic disorders" (F23). Their nosological status is unclear. The Halle-Study of acute and transient psychotic disorders (ATPD) has investigated in a prospective manner clinical, para-clinical features and course of illness in 42 patients with ATPD and matched controls with positive schizophrenia, bipolar schizoaffective disorders as well as mentally healthy patients with acute surgical conditions. First results of our study show that ATPD amount to 4% of psychotic in-patients, prefer female sex, show short prodromi, marked affective disturbances within the episode and much better outcome as schizophrenic psychoses according to psychopathological, social, psychological and biographical criteria. Though ATPD may still be an inhomogeneous group, their clinical delineation from schizophrenia seems justified.
不同国家和不同精神病学派都描述过具有急性起病、症状显著且多样以及迅速缓解特点的精神障碍。它们被称作循环性精神病、急性谵妄性精神病、心因性精神病或预后良好的精神分裂症。国际疾病分类第十版(ICD - 10)以“急性短暂性精神病性障碍”(F23)之名给出了一个操作性定义。它们的疾病分类地位尚不明确。哈雷急性短暂性精神病性障碍(ATPD)研究对42例ATPD患者以及匹配的阳性精神分裂症、双相分裂情感性障碍患者和患有急性外科疾病的心理健康患者的临床、准临床特征及病程进行了前瞻性研究。我们研究的初步结果显示,ATPD占精神病住院患者的4%,女性居多,前驱期短,发作期内有明显的情感障碍,并且根据精神病理学、社会、心理和传记学标准,其预后比精神分裂症性精神病好得多。尽管ATPD可能仍是一个异质性群体,但将它们与精神分裂症进行临床区分似乎是合理的。