Marneros Andreas, Pillmann F, Haring A, Balzuweit S, Blöink R
Klinik und Poliklinik für Psychiatrie und Psychotherapie, Martin-Luther-Universität Halle-Wittenberg, 06097 Halle, Germany.
Eur Arch Psychiatry Clin Neurosci. 2003 Aug;253(4):167-74. doi: 10.1007/s00406-003-0420-y.
Little is known about acute and transient psychotic disorders (ATPD), a diagnostic category introduced with ICD-10.
To determine the clinical and sociodemographic features, course and outcome of ICD-10 ATPD in a prospective and longitudinal study.
We recruited all consecutive inpatients fulfilling the ICD-10 criteria of ATPD during a 5-year period. Demographic and clinical features were systematically evaluated and follow-up investigations were carried out at an average of 10 years after onset of the disorder using standardized instruments.
ATPD patients represented 8.5% of all inpatients with non-organic psychotic disorders. ATPD were characterized by female preponderance. In two-thirds of the cases a typical polymorphic symptomatology was found. In spite of the fact that the possibility of relapse within 5 years was high, the psychopathological and social outcome for most of the patients was very favourable. Schizophrenic episodes during follow-up were rare (7.7% of patients), but a strictly monomorphous course (ATPD episodes only) from index episode to the end of the prospective follow-up was found in only 53.9% of the patients.
ATPD are not a sharply demarcated and unchanging nosological entity. Nevertheless, the present data support a delineation of ATPD as a diagnostic category with specific clinical features and with a usually favourable prognosis. Further research on the topic is necessary.
急性短暂性精神病性障碍（ATPD）是国际疾病分类第十版（ICD - 10）引入的一个诊断类别，对此了解甚少。
通过一项前瞻性纵向研究确定ICD - 10中ATPD的临床和社会人口学特征、病程及转归。
我们招募了在5年期间所有符合ICD - 10中ATPD标准的连续住院患者。系统评估了人口统计学和临床特征，并在疾病发作后平均10年使用标准化工具进行随访调查。
ATPD患者占所有非器质性精神病性障碍住院患者的8.5%。ATPD的特点是女性居多。在三分之二的病例中发现了典型的多形性症状。尽管5年内复发的可能性很高，但大多数患者的精神病理学和社会转归非常良好。随访期间精神分裂症发作很少见（占患者的7.7%），但从前驱发作到前瞻性随访结束只有53.9%的患者呈现严格的单形性病程（仅ATPD发作）。
ATPD不是一个界限分明且一成不变的疾病实体。然而，目前的数据支持将ATPD划定为一个具有特定临床特征且通常预后良好的诊断类别。对此主题有必要进行进一步研究。
