Rawson R, Huber A, Brethen P, Obert J, Gulati V, Shoptaw S, Ling W
UCLA Integrated Substance Abuse Programs, Los Angeles, California 90025, USA.
J Psychoactive Drugs. 2000 Apr-Jun;32(2):233-8. doi: 10.1080/02791072.2000.10400234.
The use of methamphetamine and cocaine have both produced significant public health problems during the past two decades. Although these powerful psychostimulants have many common acute and chronic effects, there are some important differences in who uses these drugs and the consequences of their use. This article reports on two large cohorts of treatment-seeking cocaine and methamphetamine users who entered treatment at the same facility over the same four-year period of time. Patterns of use differed significantly. Cocaine users have more episodic use patterns, spend more money on purchasing their drugs, and use alcohol more heavily. Methamphetamine users include a higher proportion of women, more frequently use on a daily basis, use marijuana more often, and experience more severe medical and psychiatric consequences. Despite the differences in the stimulant drug effects and consequences, the treatment response to a multicomponent, outpatient program is very similar.
在过去二十年中,甲基苯丙胺和可卡因的使用都引发了严重的公共卫生问题。尽管这些强效精神兴奋剂有许多共同的急性和慢性影响,但在使用这些药物的人群以及使用后果方面存在一些重要差异。本文报告了两组大型寻求治疗的可卡因和甲基苯丙胺使用者队列,他们在同一四年期间进入同一机构接受治疗。使用模式有显著差异。可卡因使用者有更多的间歇性使用模式,在购买毒品上花费更多,并且饮酒量更大。甲基苯丙胺使用者中女性比例更高,更频繁地每日使用,更经常使用大麻,并且经历更严重的医学和精神后果。尽管兴奋剂药物的作用和后果存在差异,但对多成分门诊项目的治疗反应非常相似。