Petry Nancy M, Peirce Jessica M, Stitzer Maxine L, Blaine Jack, Roll John M, Cohen Allan, Obert Jeanne, Killeen Therese, Saladin Michael E, Cowell Mark, Kirby Kimberly C, Sterling Robert, Royer-Malvestuto Charlotte, Hamilton John, Booth Robert E, Macdonald Marilyn, Liebert Marc, Rader Linda, Burns Raynetta, DiMaria Joan, Copersino Marc, Stabile Patricia Quinn, Kolodner Ken, Li Rui
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, USA.
Arch Gen Psychiatry. 2005 Oct;62(10):1148-56. doi: 10.1001/archpsyc.62.10.1148.
Contingency management interventions that provide tangible incentives based on objective indicators of drug abstinence are efficacious in improving outcomes in substance abusers, but these treatments have rarely been implemented in community-based settings.
To evaluate the efficacy of an abstinence-based contingency management intervention as an addition to usual care in community treatment settings.
Random assignment to usual care or usual care plus abstinence-based incentives for 12 weeks.
Eight community-based outpatient psychosocial drug abuse treatment programs.
A total of 415 cocaine or methamphetamine users beginning outpatient substance abuse treatment.
All participants received standard care, and those assigned to the abstinence-based incentive condition also earned chances to win prizes for submitting substance-free urine samples; the chances of winning prizes increased with continuous time abstinent.
Retention, counseling attendance, total number of substance-free samples provided, percentage of stimulant- and alcohol-free samples submitted, and longest duration of confirmed stimulant abstinence.
Participants assigned to the abstinence-based incentive condition remained in treatment for a mean +/- SD of 8.0 +/- 4.2 weeks and attended a mean +/- SD of 19.2 +/- 16.8 counseling sessions compared with 6.9 +/- 4.4 weeks and 15.7 +/- 14.4 sessions for those assigned to the usual care condition (P<.02 for all). Participants in the abstinence-based incentive condition also submitted significantly more stimulant- and alcohol-free samples (P<.001). The abstinence-based incentive group was significantly more likely to achieve 4, 8, and 12 weeks of continuous abstinence than the control group, with odds ratios of 2.5, 2.7, and 4.5, respectively. However, the percentage of positive samples submitted was low overall and did not differ between conditions.
The abstinence-based incentive procedure, which provided a mean of 203 dollars in prizes per participant, was efficacious in improving retention and associated abstinence outcomes.
基于药物戒断客观指标提供切实奖励的应急管理干预措施,在改善药物滥用者的治疗效果方面是有效的,但这些治疗方法在社区环境中很少实施。
评估基于戒断的应急管理干预措施作为社区治疗环境中常规护理补充的疗效。
随机分配接受常规护理或常规护理加基于戒断的奖励,为期12周。
八个社区门诊心理社会药物滥用治疗项目。
共有415名开始门诊药物滥用治疗的可卡因或甲基苯丙胺使用者。
所有参与者均接受标准护理,被分配到基于戒断奖励条件的参与者,还可因提交无药物尿液样本而获得赢取奖品的机会;随着持续戒断时间的延长,赢取奖品的机会增加。
治疗保留率、咨询出席率、提供的无药物样本总数、提交的无兴奋剂和无酒精样本百分比,以及确认的最长兴奋剂戒断持续时间。
分配到基于戒断奖励条件的参与者平均治疗时间为8.0±4.2周,平均参加咨询课程19.2±16.8次;而分配到常规护理条件的参与者分别为6.9±4.4周和15.7±14.4次(所有P值均<0.02)。基于戒断奖励条件的参与者还提交了显著更多的无兴奋剂和无酒精样本(P<0.001)。与对照组相比,基于戒断奖励组实现连续4周、8周和12周戒断的可能性显著更高,优势比分别为2.5、2.7和4.5。然而,总体提交的阳性样本百分比很低,且不同条件之间没有差异。
基于戒断的奖励程序,每位参与者平均获得203美元的奖品,在提高治疗保留率和相关戒断结局方面是有效的。