Roberts J W, Roberts C W
Proc Natl Acad Sci U S A. 1975 Jan;72(1):147-51. doi: 10.1073/pnas.72.1.147.
The bacteriophage lambda repressor, a protein that maintains the lysogenic state of a bacterium containing a lambda prophage, is cleaved when the lysogen is induced by mitomycin C or ultraviolet light. This cleavage does not occur when induction is prevented by mutational alteration either of the phage repressor or of the host recA gene product. Proteolytic cleavage may be the primary mechanism of repressor inactivation in this induction pathway, or it may follow a different event which causes the initial inactivation.
λ噬菌体阻遏物是一种维持含有λ原噬菌体的细菌溶原状态的蛋白质，当溶原菌被丝裂霉素C或紫外线诱导时，它会被裂解。当噬菌体阻遏物或宿主recA基因产物发生突变改变从而阻止诱导时，这种裂解不会发生。蛋白水解裂解可能是该诱导途径中阻遏物失活的主要机制，也可能是在导致初始失活的不同事件之后发生的。
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