Escaño M F, Fujii S, Ishibashi K, Matsuo H, Yamamoto M
The Retina Clinic, Department of Ophthalmology, Kobe University Hospital School of Medicine, Kobe, Japan.
Jpn J Ophthalmol. 2000 May-Jun;44(3):313-6. doi: 10.1016/s0021-5155(99)00224-5.
Fifty patients diagnosed with choroidal neovascularization in age-related macular degeneration were examined by indocyanine green videoangiography. Results were correlated with fundus photographs and fluorescein angiograms. Two patients were diagnosed with the macular variant of idiopathic polypoidal choroidal vasculopathy.
Two middle-aged hypertensive women were diagnosed with macular idiopathic polypoidal choroidal vasculopathy. Throughout the follow-up period, both cases showed improved signs and symptoms without worsening of visual acuity, and despite the absence of definitive therapy.
Indocyanine green videoangiography demonstrated the characteristic polypoidal lesions in idiopathic polypoidal choroidal vasculopathy better than fluorescein angiography, particularly when blood, exudates, or pigment epithelial detachments blocked visualization of the lesions.
Incidence of idiopathic polypoidal choroidal vasculopathy may not be as low as reported, as its presentation mimics choroidal neovascularization in age-related macular degeneration. Differentiation can be made only through indocyanine green videoangiography. Conservative management may be beneficial, as visual prognosis is good.
对50例年龄相关性黄斑变性合并脉络膜新生血管形成的患者进行了吲哚青绿血管造影检查。结果与眼底照片及荧光素血管造影结果进行了对比。两名患者被诊断为特发性息肉状脉络膜血管病变的黄斑变异型。
两名中年高血压女性被诊断为黄斑特发性息肉状脉络膜血管病变。在整个随访期间，尽管未进行确切治疗，但两例患者的体征和症状均有改善，且视力未恶化。
吲哚青绿血管造影比荧光素血管造影能更好地显示特发性息肉状脉络膜血管病变的特征性息肉样病变，尤其是当血液、渗出物或色素上皮脱离遮挡病变的可视性时。
特发性息肉状脉络膜血管病变的发病率可能不像报道的那么低，因为其表现类似于年龄相关性黄斑变性中的脉络膜新生血管形成。只有通过吲哚青绿血管造影才能进行鉴别。由于视觉预后良好，保守治疗可能有益。
