Slott R I, Zeweiman B
J Allergy Clin Immunol. 1975 Apr;55(4):232-40. doi: 10.1016/0091-6749(75)90142-6.
In a controlled study, a 1-week course of a moderate dosage of corticosteroids given to ragweed-sensitive subjects was associated with a statistically significant decrease in blood eosinophi, levels and tissue esosinophil, but not mast cell, responses to ragweed antibody levels or gross whealing responses to antigen or compound 48/80. While these findings suggest indirectly that a major component of the corticosteroid effect is likely an alteration of the mobilization of eosinophils to the inflammatory site, additional studies will be required to more directly characterize the mechanisms involved.
在一项对照研究中，给豚草敏感受试者服用中等剂量皮质类固醇1周，结果显示血液嗜酸性粒细胞水平和组织嗜酸性粒细胞对豚草抗体水平的反应以及对抗原或化合物48/80的明显风团反应均有统计学显著下降，但肥大细胞反应无此变化。虽然这些发现间接表明皮质类固醇作用的主要成分可能是嗜酸性粒细胞向炎症部位迁移的改变，但仍需要更多研究来更直接地描述其中涉及的机制。
