Wu N, Lü N, Chen Y
Department of Diagnostic Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing.
Zhonghua Zhong Liu Za Zhi. 1997 Nov;19(6):434-6.
To study if there are characteristic radiologic features of adenosquamous carcinoma (ASC) of the lung and correlations of histo-pathologic components with radiologic findings and prognosis.
Fifty one pathologicall confirmed ASC cases (52 foci) were reviewed. All had chest radiographs, CT scans were available in 23 cases and MRI in 6 cases. These cases were subdivided into three groups according to the amount of adenocarcinoma component on microscopic manifestations: less than 40%, 40%-60%, and more than 60%.
(1) Radiologic findings: In three cases, the tumor was of central type and in 48 cases (94.1%) of peripheral type. The size of tumor varied from 2 to 15 cm in diameter (mean, 5.7 cm). All the peripheral tumors were lobulated. In 19 cases (39.6%) the tumors were well demarcated, but poorly defined in 18 cases (19 foci) (37.5%) and spiculated in 14 cases (29.2%). Eccentric cavities with thickened wall were seen in 8 cases (15.7%) and pleural tag in 12 cases (25%). (2) Correlations between the amount of adenocarcinoma component and radiologic features: There were no statistically significant differences among the three groups with regard to tumor location, margin, and pleural tag.
The radiologic findings of ASC are not specific; the most common finding is a peripheral mass. The amount of adenocarcinoma component is not significantly related with the radiologic features and prognosis.
研究肺腺鳞癌（ASC）是否存在特征性影像学表现，以及组织病理学成分与影像学表现和预后的相关性。
回顾51例经病理确诊的ASC病例（52个病灶）。所有病例均有胸部X线片，23例有CT扫描，6例有MRI检查。根据显微镜下腺癌成分的比例将这些病例分为三组：小于40%、40%-60%和大于60%。
（1）影像学表现：3例肿瘤为中央型，48例（94.1%）为周围型。肿瘤大小直径为2至15厘米（平均5.7厘米）。所有周围型肿瘤均呈分叶状。19例（39.6%）肿瘤边界清晰，18例（19个病灶）（37.5%）边界不清，14例（29.2%）有毛刺。8例（15.7%）可见壁厚增厚的偏心空洞，12例（25%）有胸膜牵拉。（2）腺癌成分比例与影像学特征的相关性：三组在肿瘤位置、边界和胸膜牵拉方面无统计学显著差异。
ASC的影像学表现不具有特异性；最常见的表现是周围型肿块。腺癌成分比例与影像学特征和预后无显著相关性。
