Sugiyama M, Atomi Y
First Department of Surgery, Kyorin University School of Medicine, Shinkawa, Mitaka, Tokyo, Japan.
Gastrointest Endosc. 2000 Aug;52(2):187-91. doi: 10.1067/mge.2000.107285.
Little information is available on the outcomes of endoscopic sphincterotomy for choledocholithiasis in patients of advanced age (>/=90 years).
Endoscopic sphincterotomy was performed for choledocholithiasis in 22 patients aged 90 years or more (group A) and 381 aged 70 to 89 years (group B). Clinical features and early outcomes of endoscopic sphincterotomy were compared between the two groups. In group A, long-term results for a mean follow-up period of 33 months were assessed.
Group A patients had a higher incidence of symptoms, acute cholangitis and concomitant diseases, as well as larger and more numerous gallstones than did group B patients. Endoscopic sphincterotomy was technically successful in 100% of group A patients and 98% of group B patients. The rate of early complications was low in both groups: 5% in group A and 7% in group B. No deaths related to endoscopic retrograde cholangiopancreatography occurred in group A patients. Complete stone clearance was achieved in 86% of group A patients and 95% of group B patients. Group A required an emergency procedure, general anesthesia, multiple sessions, mechanical lithotripsy, and permanent biliary stent placement more frequently than group B. Late complications occurred in 5% of group A patients.
Endoscopic sphincterotomy is safe and effective for the treatment of choledocholithiasis in patients 90 years of age or older. Biliary stent placement is a reasonable alternative treatment when stones prove to be difficult to extract.
关于高龄(≥90岁)患者胆总管结石内镜括约肌切开术的结果,可获取的信息较少。
对22例90岁及以上患者(A组)和381例70至89岁患者(B组)进行了胆总管结石内镜括约肌切开术。比较两组内镜括约肌切开术的临床特征和早期结果。对A组患者进行了平均33个月的长期结果评估。
A组患者的症状、急性胆管炎和伴随疾病的发生率更高,胆结石也更大、更多,比B组患者多。内镜括约肌切开术在A组100%的患者和B组98%的患者中技术成功。两组早期并发症发生率均较低:A组为5%,B组为7%。A组患者未发生与内镜逆行胰胆管造影相关的死亡。A组86%的患者和B组95%的患者结石完全清除。A组比B组更频繁地需要急诊手术、全身麻醉、多次手术、机械碎石术和永久性胆管支架置入。A组5%的患者发生晚期并发症。
内镜括约肌切开术治疗90岁及以上患者胆总管结石安全有效。当结石难以取出时,胆管支架置入是一种合理的替代治疗方法。