Jalal Mustafa, Khan Amaan, Ijaz Sijjad, Gariballa Mohammed, El-Sherif Yasser, Al-Joudeh Amer
Department of Gastroenterology, Northern General Hospital, Sheffield, UK.
Clin Endosc. 2023 Jan;56(1):92-99. doi: 10.5946/ce.2022.020. Epub 2023 Jan 5.
BACKGROUND/AIMS: There are few studies assessed the efficacy and mortality of endoscopic retrograde cholangiopancreatography (ERCP) for the removal of common bile duct (CBD) stones in the elderly aged ≥90 years. We aimed to assess the safety and efficacy of endoscopic removal of CBD stones in nonagenarians.
We retrospectively reviewed ERCP reports for CBD stone removal. The endoscopic and therapeutic outcomes were collected. The length of stay (LOS), the total number of adverse events, and mortality rate were compared between groups.
A total of 125 nonagenarians were compared with 1,370 controls (65-89 years old individuals). The mean LOS for nonagenarians was significantly higher than in controls (13.6 days vs. 6.5 days). Completed intended treatment was similar in the nonagenarians and controls (89.8% and 89.5%, respectively). The overall complication rate did not differ between the groups. However, nonagenarians had a higher incidence of post-ERCP pneumonia (3.9%). None of the nonagenarians were readmitted to the hospital within 7 days. Four nonagenarians (3.2%) and 25 (1.8%) controls died within 30 days.
Advanced age alone did not affect the decision to perform the procedure. However, prompt diagnosis and treatment of post-ERCP pneumonia in nonagenarians could improve the outcomes and reduce mortality.
背景/目的:很少有研究评估内镜逆行胰胆管造影术(ERCP)在90岁及以上老年人中用于清除胆总管结石的疗效和死亡率。我们旨在评估非agenarians中内镜下清除胆总管结石的安全性和疗效。
我们回顾性分析了ERCP清除胆总管结石的报告。收集了内镜和治疗结果。比较了两组之间的住院时间(LOS)、不良事件总数和死亡率。
共将125名非agenarians与1370名对照组(65-89岁个体)进行了比较。非agenarians的平均住院时间显著高于对照组(13.6天对6.5天)。非agenarians和对照组的完成预期治疗情况相似(分别为89.8%和89.5%)。两组之间的总体并发症发生率没有差异。然而,非agenarians的ERCP后肺炎发生率较高(3.9%)。没有非agenarians在7天内再次入院。4名非agenarians(3.2%)和25名(1.8%)对照组在30天内死亡。
仅高龄本身并不影响进行该手术的决策。然而,及时诊断和治疗非agenarians的ERCP后肺炎可以改善预后并降低死亡率。