Giordano J, Harken A
Am Surg. 1975 Apr;41(4):221-4.
Ten mongrel dogs were placed on 5 and 10 cm. H20 of CPPV. Cardiac output, pulmonary vascular resistance and pleural pressures were measured. At 5 cm. H20/CPPV there was no significant change in cardiac output or pulmonary vascular resistance. At 10 cm. H20 CPPV cardiac output significantly decreased and pulmonary vascular resistance increased. The physiologic basis for these changes is discussed and related to the clinical situation.
十只杂种犬被置于5厘米水柱和10厘米水柱的持续气道正压通气（CPPV）环境中。测量心输出量、肺血管阻力和胸膜压力。在5厘米水柱/CPPV时，心输出量或肺血管阻力无显著变化。在10厘米水柱CPPV时，心输出量显著降低，肺血管阻力增加。讨论了这些变化的生理基础并将其与临床情况相关联。
