Post A T, Voorhorst G, Zanen A L
Sint Franciscus Gasthuis, Department of Internal Medicine, Rotterdam, The Netherlands.
Neth J Med. 2000 Aug;57(2):58-61. doi: 10.1016/s0300-2977(00)00044-9.
Omeprazole is a proton pump inhibitor widely used in the treatment of gastro-esophageal reflux disease and peptic ulcer disease. In a 73-year-old man we describe renal failure due to acute interstitial nephritis after use of omeprazol during 4 months. Unexpected renal failure without signs of hydronephrosis should always provoke awareness of drug reaction, omeprazole being one of the possible drugs.