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使用局部类固醇对儿童包茎进行保守治疗。

Conservative treatment of phimosis in children using a topical steroid.

作者信息

Orsola A, Caffaratti J, Garat J M

机构信息

Department of Pediatric Urology, Fundacio Puigvert, Barcelona, Spain.

出版信息

Urology. 2000 Aug 1;56(2):307-10. doi: 10.1016/s0090-4295(00)00576-8.

Abstract

OBJECTIVES

From 1997 through 1998, we conducted a prospective study to evaluate the long-term outcome of using topical steroids in the treatment of childhood phimosis.

METHODS

Both the parents and their children were instructed to apply 0.05% betamethasone cream topically twice a day for 1 month and to retract the prepuce after the fifth day of treatment. Results were evaluated at the end of the treatment and 6 months later.

RESULTS

One hundred thirty-seven boys were evaluated. The median age was 5.4 years. At initial presentation, 61 boys had a phimotic but retractable prepuce, 37 had a nonretractable phimotic ring, and 39 had a pinpoint opening. Patients with a history of previous forcible foreskin retractions were considered to have secondary phimosis. By 6 months following treatment, 90% (124 children) had an easily retractable prepuce without a phimotic ring. No differences were seen in the response rate between those with primary and secondary phimosis. In all cases, the treatment was well tolerated without local or systemic side effects. All the patients with persistent or recurrent phimosis were found to be noncompliant with the suggested daily foreskin care.

CONCLUSIONS

Topical steroid for the treatment of phimosis is a safe, simple, and inexpensive procedure that avoids surgery and its associated risks. It is effective both in primary and in secondary phimosis. We emphasize the importance of proper and regular foreskin care and hypothesize on the mechanism of action of the steroids.

摘要

目的

从1997年至1998年,我们进行了一项前瞻性研究,以评估外用类固醇治疗儿童包茎的长期疗效。

方法

指导家长及其孩子每天两次外用0.05%倍他米松乳膏,持续1个月,并在治疗第5天后翻开包皮。在治疗结束时和6个月后评估结果。

结果

对137名男孩进行了评估。中位年龄为5.4岁。初次就诊时,61名男孩包皮包茎但可翻开,37名有不可翻开的包茎环,39名有针孔样开口。有既往强行翻开包皮病史的患者被视为继发性包茎。治疗6个月后,90%(124名儿童)的包皮可轻松翻开,无包茎环。原发性和继发性包茎患者的有效率无差异。在所有病例中,治疗耐受性良好,无局部或全身副作用。所有持续性或复发性包茎患者均被发现未遵循建议的每日包皮护理。

结论

外用类固醇治疗包茎是一种安全、简单且廉价的方法,可避免手术及其相关风险。它对原发性和继发性包茎均有效。我们强调适当和定期进行包皮护理的重要性,并对外用类固醇的作用机制提出假设。

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