Hayashi N, Ishii K, Kitagaki H, Kazui H
Department of Radiology, Kobe University School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe, Hyogo, Japan.
J Neurol Sci. 2000 Jun 15;176(2):102-8. doi: 10.1016/s0022-510x(00)00323-3.
Regional cerebral differences in activation by two types of calculation, quantitative number processing and use of rote verbal arithmetic memory, were investigated.
The two types of processing were induced by serial number subtraction (the Subtra-task) and recitation of the multiplication table (the Multi-task), respectively. Regional cerebral blood flow (rCBF) under the two tasks was measured in ten healthy right-handed Japanese men using (15)O-labeled water and positron emission tomography (PET). Statistical parametric mapping (SPM) was used for estimating rCBF differences during these tasks.
The activated areas during the Subtra-task were consistent with those reported to be involved in quantitative number processing. Although most of the regions activated during the Multi-task were in common with the regions activated during the Subtra-task, the spatial extent of the activation during the Multi-task was smaller. Moreover, the left lenticular nucleus was activated during the Multi-task, but not in the Subtra-task, while the prefrontal cortex was activated in the Subtra-task but not in the Multi-task.
The difference in the regions activated by the two tasks, and the difference in the spatial extent of each region by the two tasks indicated that the anatomical networks of the two processes were segregated.
研究了两种计算方式（定量数字处理和死记硬背的口头算术记忆运用）所引起的大脑区域激活差异。
分别通过序列号减法（减法任务）和乘法口诀背诵（乘法任务）诱导这两种处理方式。使用（15）O标记水和正电子发射断层扫描（PET）对10名健康右利手日本男性在这两项任务下的局部脑血流（rCBF）进行测量。使用统计参数映射（SPM）来估计这些任务期间的rCBF差异。
减法任务期间的激活区域与据报道参与定量数字处理的区域一致。虽然乘法任务期间激活的大多数区域与减法任务期间激活的区域相同，但乘法任务期间激活的空间范围较小。此外，左豆状核在乘法任务期间被激活，而在减法任务中未被激活，而前额叶皮质在减法任务中被激活，但在乘法任务中未被激活。
两项任务激活区域的差异以及两项任务中每个区域空间范围的差异表明这两个过程的解剖网络是分开的。
