Togliatto M, Carrozzo M, Conrotto D, Pagano M, Gandolfo S
Dipartimento di Fisiopatologia Clinica, Università degli Studi, Torino.
Minerva Stomatol. 2000 Jan-Feb;49(1-2):35-40.
The aim of this study is to evaluate all the cases of lupus erythematosus with oral involvement coming to the Department of Oral Medicine in the last 15 years (1984-1998).
The files of the Oral Medicine Department of the University of Turin have been reviewed to search oral manifestations of lupus erythematosus according to international accepted diagnostic criteria.
A total of eleven patients 7 women (64%) and 4 men (36%) with a mean age of 46 years were included. Three patients (27%) had discoid lupus erythematosus (LED) whereas 8 (73%) had systemic lupus erythematosus (LES). In four patients the diagnosis of lupus was made after oral diagnosis, whereas 7 patients (64%) had a previous diagnosis of lupus. Clinical aspect was typical in 8 cases (73%) while one patient had leukoplakia-like white patches and two patients (18%) had lichen-like oral lesion.
This study suggest that primitive oral lesion of lupus are quite rare but frequently may have atypical features often difficult to differentiate from lichen planus.
本研究旨在评估过去15年（1984 - 1998年）间到口腔医学科就诊的所有口腔受累的红斑狼疮病例。
查阅了都灵大学口腔医学科的病历档案，根据国际公认的诊断标准查找红斑狼疮的口腔表现。
共纳入11例患者，其中7名女性（64%），4名男性（36%），平均年龄46岁。3例患者（27%）患有盘状红斑狼疮（DLE），而8例（73%）患有系统性红斑狼疮（SLE）。4例患者在口腔诊断后确诊为狼疮，而7例患者（64%）此前已被诊断为狼疮。8例（73%）患者的临床表现典型，1例患者有白斑样白色斑块，2例患者（18%）有苔藓样口腔损害。
本研究表明，狼疮的原发性口腔损害相当罕见，但通常可能具有非典型特征，常难以与扁平苔藓相鉴别。
