Paladin F, Capovilla G, Bonazza A, Mameli R
Division of Neurology, Ospedale Ss. Giovanni e Paolo, Venezia, Italy.
Ital J Neurol Sci. 1998 Aug;19(4):217-20. doi: 10.1007/BF02427604.
Neuroradiological examinations are important in the diagnosis of Rasmussen's syndrome (RS), but they frequently result normal in the early phase of the disease. We performed Tc 99m HMPAO SPECT (single photon emission computed tomography) on an 11-year, 5-month-old, right-handed girl, two months since the first seizure. SPECT showed a reduced uptake of HMPAO in the left temporal region despite normal results with magnetic resonance imaging (MRI). After six months, she developed epilepsia partialis continua, neurological signs appeared, and MRI showed cortical atrophy on the left side. SPECT seems to be a useful, inexpensive and diffuse technology able to give information in the early phases of RS useful in the prevention of serious consequences of the disease within a medical therapeutic program (ganciclovir or intravenous immunoglobulins).
神经放射学检查在拉斯穆森综合征（RS）的诊断中很重要，但在疾病早期其结果常常正常。我们对一名11岁5个月大的右利手女孩进行了锝99m六甲基丙二胺肟单光子发射计算机断层扫描（SPECT），该女孩自首次发作起已有两个月。尽管磁共振成像（MRI）结果正常，但SPECT显示左颞叶区域六甲基丙二胺肟摄取减少。六个月后，她出现了持续性部分性癫痫，出现了神经体征，MRI显示左侧皮质萎缩。SPECT似乎是一种有用、廉价且广泛应用的技术，能够在RS的早期阶段提供信息，这对于在医学治疗方案（更昔洛韦或静脉注射免疫球蛋白）中预防该疾病的严重后果很有用。
