Reoux J P, Miller K
VA Puget Sound Health Care System, Seattle, Wash. 98108, USA.
Am J Addict. 2000 Spring;9(2):135-44. doi: 10.1080/10550490050173208.
Charts of patients hospitalized for uncomplicated alcohol withdrawal were examined and detoxification practices compared. Patients detoxified using a Clinical Institute Withdrawal Assessment for Alcohol-revised (CIWA-Ar) based PRN protocol on the addiction unit received significantly fewer chlordiazepoxide milligram equivalents over shorter duration than patients managed by other detoxification methods on other hospital units. Significantly fewer patients received benzodiazepines in the CIWA-Ar protocol managed group, but inter-group differences (p < 0.01) remained when only medicated patients were compared. Differences between the protocol and non-protocol groups did not reach statistical significance when PRN only strategies were examined, suggesting that the use of a symptom-triggered strategy may account for the noted effects.
对因单纯酒精戒断而住院的患者病历进行了检查,并比较了脱毒治疗方法。在成瘾科,使用基于酒精戒断临床研究所修订评估量表(CIWA-Ar)的按需给药方案进行脱毒治疗的患者,在较短时间内接受的氯氮卓毫克当量显著少于在其他医院科室采用其他脱毒方法治疗的患者。在采用CIWA-Ar方案治疗的组中,接受苯二氮卓类药物的患者明显较少,但仅比较用药患者时,组间差异(p<0.01)仍然存在。当仅检查按需给药策略时,方案组和非方案组之间的差异未达到统计学显著性,这表明使用症状触发策略可能是上述效果的原因。