Shimada H, Isomae T, Shimizu S, Yuzawa M
Department of Ophthalmology, Surugadai Hospital of Nihon University, Tokyo, Japan.
Nippon Ganka Gakkai Zasshi. 2000 Jul;104(7):489-94.
We investigated the influence of various factors on visual results in patients undergoing surgical removal of choroidal neovascular membranes (CNVM) caused by age-related macular degeneration (AMD).
This study was performed in 55 eyes of 55 patients who underwent surgical removal of CNVM for AMD and followed them for 6 months or more. The criterion for surgical eligibility was active subfoveal choroidal neovascular membrane of 0.5 or more disc diameter above the retinal pigment epithelium with visual acuity of 0.3 or worse. We investigated the influence of various factors on the logarithm of the minimum angle of resolution (log MAR) final visual acuity. The factors were age, symptom duration, preoperative log MAR visual acuity, CNVM diameter, mean deviation with visual field analyzer, previous laser treatment, posterior vitreous detachment, findings of indocyanine green angiography, operative complications, and recurrence of CNVM.
Better preoperative visual acuity, shorter symptom duration, and smaller CNVM diameter were correlated with better postoperative final visual acuity.
Surgical excision of subfoveal CNVM may be the better therapeutic choice in selected cases with AMD.
我们研究了各种因素对因年龄相关性黄斑变性(AMD)接受脉络膜新生血管膜(CNVM)手术切除患者视觉结果的影响。
本研究对55例因AMD接受CNVM手术切除的患者的55只眼进行,随访6个月或更长时间。手术适应证标准为视网膜色素上皮上方直径0.5个视盘直径或更大的活动性黄斑中心凹下脉络膜新生血管膜,视力为0.3或更差。我们研究了各种因素对最小分辨角对数(log MAR)最终视力的影响。这些因素包括年龄、症状持续时间、术前log MAR视力、CNVM直径、视野分析仪平均偏差、既往激光治疗、玻璃体后脱离、吲哚菁绿血管造影结果、手术并发症以及CNVM复发。
术前视力更好、症状持续时间更短以及CNVM直径更小与术后最终视力更好相关。
对于某些AMD病例,黄斑中心凹下CNVM的手术切除可能是更好的治疗选择。