Le Frock J, Ellis C A, Klainer A S, Weinstein L
Arch Intern Med. 1975 Jun;135(6):835-7. doi: 10.1001/archinte.135.6.835.
A group of 175 patients had barium enema. Pour-plate blood cultures were obtained immediately before and after the procedure and 5, 10, 15, and 30 minutes later. Bacteremia was demonstrable in 20 (11.4%) patients. In some, blood cultures were positive for as long as 15 minutes after barium enema; all were negative at 30 minutes. Among the bacteria associated with the 20 episodes of bacteremia were Escherichia coli, Klebsiella, enterococci, Proteus morganii, Bacteroides, and Veillonella. The incidence of bacteremia among patients with ulcerative colitis, regional enteritis, rectal polyps, colonic or rectal carcinoma, nonspecific diarrhea, or other lower intestinal tract disorders was not much different from patients free of rectosigmoid disease. The results of this study suggest that a history of recent barium enema may be important in patients who have endocarditis.
175名患者接受了钡灌肠检查。在检查前后即刻以及检查后5分钟、10分钟、15分钟和30分钟采集倾注平板血培养标本。20名（11.4%）患者出现菌血症。部分患者在钡灌肠后长达15分钟血培养呈阳性；30分钟时所有血培养均为阴性。与这20次菌血症相关的细菌包括大肠杆菌、克雷伯菌、肠球菌、摩根变形杆菌、拟杆菌和韦荣球菌。溃疡性结肠炎、局限性肠炎、直肠息肉、结肠或直肠癌、非特异性腹泻或其他下肠道疾病患者的菌血症发生率与无直肠乙状结肠疾病的患者相比并无太大差异。本研究结果提示，近期有钡灌肠史对于患有心内膜炎的患者可能很重要。
