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Analogs of luteinizing hormone releasing factor (LRF). Synthesis and biological activity of ((Nalpha-Me)Leu-7)LRF and (D-Ala-6,(Nalpha-Me)Leu-7)LRF.

作者信息

Ling N, Vale W

出版信息

Biochem Biophys Res Commun. 1975 Apr 7;63(3):801-6. doi: 10.1016/s0006-291x(75)80454-2.

DOI:10.1016/s0006-291x(75)80454-2
PMID:1093545
Abstract
摘要

相似文献

1
Analogs of luteinizing hormone releasing factor (LRF). Synthesis and biological activity of ((Nalpha-Me)Leu-7)LRF and (D-Ala-6,(Nalpha-Me)Leu-7)LRF.促黄体生成素释放因子(LRF)类似物。((Nα-甲基)亮氨酸-7)LRF和(D-丙氨酸-6,(Nα-甲基)亮氨酸-7)LRF的合成及生物活性
Biochem Biophys Res Commun. 1975 Apr 7;63(3):801-6. doi: 10.1016/s0006-291x(75)80454-2.
2
Synthetic analogs of luteinizing hormone releasing hormone (LH-RH) substituted in position 6 and 10.在第6位和第10位被取代的促黄体生成素释放激素(LH-RH)的合成类似物。
Biochem Biophys Res Commun. 1974 Sep 9;60(1):406-13. doi: 10.1016/0006-291x(74)90219-8.
3
Synthesis and biological activities of analogs of the luteinizing hormone-releasing hormone (LH-RH) modified in position 2.在第2位进行修饰的促黄体生成激素释放激素(LH-RH)类似物的合成及生物活性
J Med Chem. 1974 Sep;17(9):1016-9. doi: 10.1021/jm00255a025.
4
Synthesis and biological properties of (Leu-6)-LH-RH and (D-Leu-6,desGly-NH210)-LH-RH ethylamide.
Biochem Biophys Res Commun. 1974 Aug 19;59(4):1226-32. doi: 10.1016/0006-291x(74)90445-8.
5
Synthetic analogs of the hypothalamic luteinizing hormone releasing factor with increased agonist or antagonist properties.具有增强激动剂或拮抗剂特性的下丘脑促黄体生成激素释放因子的合成类似物。
Biochemistry. 1973 Nov 6;12(23):4616-20. doi: 10.1021/bi00747a012.
6
Synthesis and biological activity of some analogs of the gonadotropin releasing hormone.一些促性腺激素释放激素类似物的合成与生物活性
J Med Chem. 1974 Mar;17(3):314-9. doi: 10.1021/jm00249a012.
7
Further studies on the structure-activity relationships in the C-terminal part of luteinizing hormone-releasing hormone.
J Med Chem. 1973 Oct;16(10):1144-7. doi: 10.1021/jm00268a017.
8
Some analogs of luteinizing hormone releasing hormone (LH-RH) having intense ovulation-inducing activity.
Biochem Biophys Res Commun. 1974 Apr 23;57(4):1248-56. doi: 10.1016/0006-291x(74)90830-4.
9
Analogues of luteinizing hormone releasing factor modified at positions 2, 6, and 10.在第2、6和10位进行修饰的促黄体生成激素释放因子类似物。
J Med Chem. 1976 Jul;19(7):937-41. doi: 10.1021/jm00229a016.
10
Synthetic luteinizing hormone releasing factor. Short chain analogs.
J Med Chem. 1974 Feb;17(2):230-3. doi: 10.1021/jm00248a019.

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Iterative approach to the discovery of novel degarelix analogues: substitutions at positions 3, 7, and 8. Part II.新型地加瑞克类似物发现的迭代方法:3、7和8位的取代。第二部分。
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Gonadotrophin-releasing hormone agonists. A guide to use and selection.促性腺激素释放激素激动剂。使用与选择指南。
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Decapeptides as effective agonists from L-amino acids biologically equivalent to the luteinizing hormone-releasing hormone.作为与促黄体生成素释放激素生物等效的L-氨基酸有效激动剂的十肽。
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5
Isolation, primary structure, and synthesis of alpha-endorphin and gamma-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity.α-内啡肽和γ-内啡肽的分离、一级结构及合成,这两种源于下丘脑 - 垂体且具有吗啡样活性的肽。
Proc Natl Acad Sci U S A. 1976 Nov;73(11):3942-6. doi: 10.1073/pnas.73.11.3942.
6
Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.β-促脂素合成片段及类似物的拟吗啡活性
Proc Natl Acad Sci U S A. 1976 Sep;73(9):3308-10. doi: 10.1073/pnas.73.9.3308.