恶性疟通过奎宁治疗后再用磺胺多辛-乙胺嘧啶治愈。
Falciparum malaria cured by quinine followed by sulfadoxine-pyrimethamine.
作者信息
Hall A P, Doberstyn E B, Mettaprakong V, Sonkom P
出版信息
Br Med J. 1975 Apr 5;2(5961):15-7. doi: 10.1136/bmj.2.5961.15.
Abstract
Quinine (at least four doses given at intervals of eight to 12 hours) followed by a single dose of sulfadoxine-pyrimethamine (Fansidar) is the most effective treatment of chloroquine-resistant falciparum malaria. This regimen cured 96% of patients (302 out of 314) with an average initial parasite count of 90 X 10-9/1.
摘要
奎宁（至少分四剂，每隔八至十二小时服用一剂），随后单剂量服用周效磺胺-乙胺嘧啶（Fansidar），是治疗对氯喹耐药的恶性疟最有效的方法。该疗法治愈了96%的患者（314例中的302例），这些患者的初始寄生虫平均计数为90×10⁻⁹/升。
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