硝酸咪康唑与氯己定治疗阴道念珠菌病的比较。
Miconazole nitrate compared with chlordantoin in the treatment of vaginal candidiasis.
作者信息
Morris D F, Sugrue D L
出版信息
Br J Vener Dis. 1975 Apr;51(2):123-4. doi: 10.1136/sti.51.2.123.
In a double-blind study of the treatment of vaginal candidiasis, miconazole nitrate gave a cure-rate of 88 per cent. (29 out of 33) compared with 58 per cent. (21 out of 36) using chlordantoin. Although approximately two-thirds of the patients who responded did so to a 10-day course of treatment, the different rates of cure with these preparations at this stage were not statistically significant. However, when a second course of treatment was given to those women who still had proven candidiasis, the overall cure-rate with miconazole was significantly greater than that with chlordantoin.
在一项关于阴道念珠菌病治疗的双盲研究中，硝酸咪康唑的治愈率为88%（33例中有29例），而使用氯丹妥因的治愈率为58%（36例中有21例）。虽然约三分之二有反应的患者是在接受10天疗程的治疗后出现疗效，但在这个阶段，这些制剂的不同治愈率并无统计学意义。然而，当对那些仍确诊为念珠菌病的女性给予第二个疗程的治疗时，咪康唑的总体治愈率显著高于氯丹妥因。
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